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Effects of a Personalized Retrieval-Augmented Generation Chatbot on Information Needs in Chronic Kidney Disease Patients: Mixed Methods Randomized Controlled Trial

Hee Jeong Hwang, Junghwan Kim, Dongseok Heo, Jeong Yun You, Jeonghwan Lee, Soie Kwon, Kyung Don Yoo, Jung Han Yoon Park, Bongwon Suh, Jung Pyo Lee, Ki Won Lee

Interactive Journal of Medical Research
i-JMR 2026 · Journal Article · In press

📝Overview

This journal article reports a mixed-methods randomized controlled trial of a personalized retrieval-augmented generation (RAG) chatbot for patients with chronic kidney disease. The chatbot answers patients’ questions using their own clinical information and vetted medical guidance, and the trial measures its effect on patients’ information needs alongside qualitative accounts of how they used it.

The work was carried out with nephrologists and clinical researchers at Seoul National University hospitals. My contribution centred on the design and implementation of the RAG system and its patient-facing interface. A companion CSCW poster, Between the Clinic and the Kitchen, examines the same system through the lens of boundary infrastructure. The paper is accepted and in press at the Interactive Journal of Medical Research.

The official abstract will be posted once the paper is published. This overview is a short description of the work.

Health InformaticsRetrieval-Augmented GenerationRandomized Controlled Trial

🔖BibTeX

@article{hwang2026ckdchatbot,
  title = {Effects of a Personalized Retrieval-Augmented Generation Chatbot on Information Needs in Chronic Kidney Disease Patients: Mixed Methods Randomized Controlled Trial},
  author = {Hee Jeong Hwang and Junghwan Kim and Dongseok Heo and Jeong Yun You and Jeonghwan Lee and Soie Kwon and Kyung Don Yoo and Jung Han Yoon Park and Bongwon Suh and Jung Pyo Lee and Ki Won Lee},
  journal = {Interactive Journal of Medical Research},
  year = {2026},
  doi = {10.2196/96501}
}